The Super Eagles were held to a 1-1 draw at Moshood Abiola stadium in Abuja on Tuesday after a goalless draw in Baba Yara stadium in Ghana.
This means the miss the opportunity to shine in this years world cup despite having a talented team.
Thomas Partey gave Ghana the lead 10 minutes into the game when his right footed shot from outside the box ended in the bottom left conner of the post.
William Troost-Ekong converts the penalty with a right footed shot to the bottom right corner to level the scores for Super Eagles 12 minutes later.
The first half of the World Cup qualifier second-leg encounter between Nigeria and Ghana ended 1-1.