Italy claimed their third successive 2-0 win to go three points clear at the top of Group C for now.
The visitors were the better side throughout and really upped their game after half-time, spurred by Mancini’s half-time changes.
Sensi’s goal early in the second half broke Lithuania’s resistance, and immobile’s goal finally saw them off.
Lithuania made Italy work hard for the win with Mancini’s team having whopped 29 shots in the match.
Their keeper was up to the task making a series of great saves.
Lithuania go bottom of Group C after Northern Ireland’s 0-0 draw with Bulgaria, having lost their first two games.